![]() Virani, who is affiliated with Texas Heart Institute and is vice provost for research at Aga Khan University in Pakistan, puts less stock in the details of the results because it relied on a subset of trial participants, who might not be representative. ![]() Salim Virani, who was not involved in the study, agreed with Nissen's message but was more cautious about the findings. ![]() The half who took bempedoic acid were 39% less likely to die from a cardiac event over the next three-and-a-half years than those who received a placebo, a result Nissen called "simply stunning." The study looked at a subset of 4,200 of those people, who hadn't yet had a major cardiac event like a heart attack or stroke. That finding showed in 14,000 patients that bempedoic acid was a viable alternative to statins for people who can't take the cheaper, more established drugs. The research was a follow-on to a large study looking at bempedoic acid Nissen published earlier this year. "I think that's an important message to the public." Take the findings with a grain of salt "You can get your LDL down if you can't get a statin," said Ballantyne, who was not involved in the research. Christie Ballantyne, director of the center for cardiometabolic disease prevention at Baylor College of Medicine in Houston, said he sees the study as "good news." "I think this is a wake-up call to the medical community and to patients that people who have high cholesterol and risk factors need to be treated," Nissen said.ĭr. Steven Nissen, the Cleveland Clinic cardiologist who led the new research, which is being presented Saturday at the American Diabetes Association annual conference in San Diego. But fewer than half of those at high risk are taking appropriate medication, said Dr. Having high cholesterol along with diabetes, obesity, a history of tobacco use or high blood pressure puts people at risk for heart attack and stroke. But for people who can't tolerate statins or a high enough dose to bring their cholesterol levels down enough, the new study suggests that it's important to find alternatives and that bempedoic acid can be at least part of the solution. ![]() It's far more expensive and doesn't have the decadeslong track record of safety and effectiveness. Researchers are quick to say bempedoic acid shouldn't be used instead of statins. The study looked at a statin alternative, called bempedoic acid, and found that as it reduced levels of LDL cholesterol, it also lowered the risk for heart attack, stroke and death. A new study reinforces the importance of lowering cholesterol in people at risk for but who haven't had a heart attack or stroke. ![]()
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